Dietary lactose and the aetiology of human small-intestinal hypolactasia.
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چکیده
منابع مشابه
Dietary lactose and the aetiology of human small-intestinal hypolactasia.
The only carbohydrate in milk is lactose, a disaccharide, which is formed of a molecule of glucose and a molecule of galactose. Cow's milk contains about 5 % lactose and human milk about 6'5-7 %. Lactose is hydrolysed to its monosaccharides principally by a specific enzyme, lactase, which is a f-galactosidase. There are also two other enzymes with ,3-galactosidase activitv, lysosomal acid 3-gal...
متن کاملAdult-type hypolactasia and lactose malabsorption in Poland.
BACKGROUND The available data on the incidence of lactose malabsorption are contradictory. Potential bias in random selection is a major drawback of studies performed to-date. Moreover, molecular analysis of polymorphism -13910 C>T upstream of the lactase (LCT) gene (NM_005915.4:c.1917+326C>T; rs4988235) has not been reported in those studies. Therefore, in this study we aimed to assess genetic...
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Lactase-phlorizin hydrolase (LPH), a membrane-bound glycoprotein present in the luminal surface of enterocytes in the intestine is responsible for lactose intolerance, a phenomenon prevalent in humans worldwide. In the rodent intestine, the post-natal development of the LPH follows a specific pattern, such that the enzyme levels are high in the peri-natal period, but declines considerably upon ...
متن کاملHypolactasia & lactose intolerance among three ethnic groups in Malaysia.
BACKGROUND & OBJECTIVES Prevalence of adult-type hypolactasia is known to vary among different countries and in different ethnic populations in the same country. The present study was undertaken to evaluate the prevalence of hypolactasia and lactose intolerance in three different ethnic populations living in similar environmental conditions in Malaysia. The correlation between different symptom...
متن کاملImmunoelectrophoretic studies on human small intestinal brush border proteins--amount of lactase protein in adult-type hypolactasia.
Jejunal biopsies from 15 Greenlandic and three Danish patients with adult type hypolactasia and nine Greenlandic and 15 Danish patients with normal lactase activity were analysed quantitatively for lactase protein by crossed immunoelectrophoresis. A constant correlation between the amount of lactase activity and immunologically reactive lactase protein was demonstrated irrespective of the lacta...
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ژورنال
عنوان ژورنال: Gut
سال: 1978
ISSN: 0017-5749
DOI: 10.1136/gut.19.11.1074